Importantly, the approach used by the scientists -- which led to the identification of a drug-like molecule that stopped the virus from replicating within cells -- may have broader application to other infectious diseases.This is because all intracellular pathogens rely on their host cell signalling system to replicate.HCV affects about two per cent of the world's population.Infection can lead to chronic hepatitis, which can progress to liver cirrhosis and carcinoma.An international study has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.
We had so much in common, from a love of reading to a history of youthful troublemaking.
The study, published in today, focused on protein kinases, enzymes that are key regulators of cellular processes.
It built on previous ground-breaking work on malaria published in 2011 by author Monash Professor Christian Doerig, and others, who found that if host cell protein kinases were prevented from working it would kill malaria parasites.
The survey found that about 74% of the people infected with hepatitis C believe that others think the disease only infects unhealthy people or drug addicts.
However, when uninfected people were asked, it turned out that only 30% had this impression.